Wednesday, July 18, 2018

Protein Engineering Canada Conference: A Review



Last month, leaders in the fields of protein engineering and synthetic biology met at the campus of the University of British Columbia in Vancouver, Canada, for the 3rd Protein Engineering Canada (PEC) Conference 2018. The PEC Conference encourages the exchange of ideas and aims to build collaborations in an engaging atmosphere by bringing together students, young investigators, and protein engineering experts. SGI-DNA was a proud contributor to the conference and hosted a lunch seminar entitled “Emerging Technologies: Library Construction using the BioXp™ 3200 System,” presented by Steve Riedmuller, Sr. Director of Field Application Science.

In the well-received seminar, Riedmuller discussed advantages of using the BioXp System for library construction. The BioXp System is an automated benchtop genomic workstation that builds synthetic linear DNA fragments with powerful applications for synthetic biology. DNA libraries are vital for drug discovery, and scientists working in protein engineering, discovery biology, structural biology, synthetic biology, antibody engineering, and enzyme engineering can benefit from BioXp™ Libraries to quickly determine an optimized targeted gene. The BioXp System offers a wide array of library types, including degenerate, variant, and scanning libraries. Riedmuller described the capabilities of the BioXp System and presented a case study demonstrating how the BioXp System drastically accelerated library production when used in conjunction with Gibson Assembly® cloning for the direct transfection of synthetic constructs. Additional details of rapid library construction can be found in this Application Note.


Riedmuller also discussed how the BioXp System can be used for accelerated cancer vaccine production. Introducing genes into eukaryotic cells provides a foundation for cancer vaccines. The premise behind cancer vaccines is that the presence of neoepitopes (“new” peptides that are the result of mutations in cancer cells only) can be used as a target to trigger a patient’s own immune response to specifically attack and destroy cancer cells. One of the technical hurdles of these types of personalized medicines is the time required to prepare an individualized treatment, in this case, a cancer vaccine. Using the BioXp System to build epitopes based on the genetic profile of a patient’s tumor cells dramatically reduces the turnaround time required for creating personalized cancer vaccines, which is critically important to patients facing a terminal diagnosis and recently discussed in this Seattle Times article


The BioXp System offers a high throughput solution for protein engineering and synthetic biology applications. In the hands of the scientists in attendance at the PEC Conference (and readers of this blog), this instrument offers new opportunities for faster and more expansive research and discovery.

For more information about the products and applications mentioned in this blog post, please see:

BioXp 3200 System – sgidna.com/bxp3200
Gibson Assembly Reagents - sgidna.com/reagents.html

19 comments:

  1. Thanks Your post is so cool and this is an extraordinary moving article and If it's not too much trouble share more like that.
    Digital Marketing Course in Hyderabad

    ReplyDelete
  2. Accounting is a subject that demands much more than subject knowledge like marketing mathematics statistics of the few. So even if you are very attentive in your class, chances are you might have missed any of the lectures on the above subjects, and thus it is becoming very challenging for you to complete those accounting assignments. It is okay to look for accounting homework assignments online as they can help you fight the stress you feel due to the submission. Finding an accounting assignment help is not easy. Still, with a little due diligence, you are sure to get a finished copy that is authentically made for you by an accounting expert, this way; you will have a better chance of building the things you love to accomplish.

    ReplyDelete
  3. You have done excellent job Thanks a lot and I enjoyed your blog. Great Post.
    Ethical Hacking Course in Hyderabad

    ReplyDelete
  4. Excellent post to make this blog more wonderful, attractive and cool stuff you have. Thank You.
    Data Science Course in India with Placements

    ReplyDelete
  5. I just got to this amazing site not long ago was actually captured with the piece of resources you have got here and big thumbs up for making such wonderful blog page!
    Data Scientist Course

    ReplyDelete
  6. Very informative message! There is so much information here that can help me thank you for sharing
    Data Analytics Course in Lucknow

    ReplyDelete
  7. I am hoping the same best effort from you in the future as well and in fact your creative writing skills has inspired me.
    Data Science Course near me

    ReplyDelete
  8. Very informative blog! There is so much information here that can help thank you for sharing.
    Data Science Syllabus

    ReplyDelete
  9. Make sure the surface where you are placing the printer is clean and close to Pc or laptop.Check the shipped components with your inkjet printer
    http //ij.start.canon,
    https //ij.start.cannon

    ReplyDelete
  10. ij.start.canon
    is the manufacturer site to download Canon printer drivers. Install and set up Canon Printer from https: //ij.start.canon and obtain high-quality printing documents straightforwardly.

    https//ij.start.cannon is actually the official site of ij start canon that helps you install the latest printer drivers and software. Visiting http //ij.start.cannon
    provides you a complete list of all canon printers where you’ve to select your printer model and download the correct setup file

    ReplyDelete
  11. Canon IJ Network Tool is a toolkit software with the options to keep a check on most of your Canon printer network settings and adjust them according to your requirements.

    Canon IJ Printer Utility is a complete software package meant to adjust and modify the configurations of your printer device as per the requirement. It is one of the essential utility software offered by Canon to ease your printer configuration alteration using a few clicks.


    Canon.com/ijsetup/mg2500
    is the Canon support link to get you the latest printer drivers and software to set up your PIXMA MG2500 or MG2520.

    ReplyDelete
  12. Canon IJ Network Tool will get you through the network settings uninterruptedly. It is essentially required when you are attempting to get your printer connected to a different network because a new network tends to reset the printer’s existing network settings.The Canon IJ Printer Utility can be used to keep a check on your printer’s ink levels and cartridges and clean the ink tanks and paper feed rollers. Also, you can make adjustments to your Canon printer’s power settings.

    ReplyDelete
  13. Once you are done with the driver setup via canon.com/ijsetup , you will have to insert a pile of pages into the printer tray for printing the documents..

    Visit ij.start.canon | ij.start canon and find out the best way to download Canon printer drivers.

    All-in-one Canon Inkjet printers are suitable for home, business, school, and others to improve productivity. You can easily set up your Canon printer through drivers from Canon.com/ijsetup , wireless connection, USB, and a few components.

    ReplyDelete
  14. The ij.start.cannon setup process for every Canon model is almost similar, however the download through https //ij.start.cannon and http //ij.start.cannon installation process may differ. you can also visit canonsetup-canon.com/ijsetup website for same. Https //ij.start.cannon.Depending on your requirement, it offers a type printer including PIXMA, SELPHY, MAXIFY, etc. canon.com/ijsetup

    ReplyDelete
  15. Canon drivers fully support and assists for all compatible products for all Window versions. We offer the required data to configure, utilize and install your Canon products on your Windows PC.canon is completely safe and secure. ij.start.canon |
    ij.start.cannon

    ReplyDelete
  16. Ij start canon and find out the best way to download Canon printer drivers.
    Ij.start.cannon | Ij.start.canon | canon.com/ijsetup

    ReplyDelete
  17. It's a lovely and wonderful composition. Keep up the good work; I'm looking forward to reading more from this blog.
    green glass door game
    how late is the closest grocery store open

    ReplyDelete
  18. I have read your blog and find it very very helpful to me, thank's for sharing
    high quality guest post service

    cheap guest posting service

    ReplyDelete